From a937dfcaae61f0e80ced45a6968cdcb2cd2be17f Mon Sep 17 00:00:00 2001
From: ognome-dev <236690662+ognome-dev@users.noreply.github.com>
Date: Wed, 13 May 2026 04:50:25 +0000
Subject: [PATCH] feat(examples): add biomedical healthcare research use case

---
 examples/biomedical-research.js | 164 ++++++++++++++++++++++++++++++++
 1 file changed, 164 insertions(+)
 create mode 100644 examples/biomedical-research.js

diff --git a/examples/biomedical-research.js b/examples/biomedical-research.js
new file mode 100644
index 00000000..7b16030b
--- /dev/null
+++ b/examples/biomedical-research.js
@@ -0,0 +1,164 @@
+/**
+ * Biomedical Research Example
+ *
+ * Demonstrates publishing a healthcare knowledge asset to the OriginTrail DKG
+ * using the schema.org/MedicalStudy vocabulary with PubMed citation provenance.
+ *
+ * Use case: OpenGenome (https://opengenome.bio) publishes AI-generated biomedical
+ * research reports as verifiable knowledge assets on the DKG after minting
+ * the corresponding NFT on Solana. This creates a dual-anchor for each report:
+ * one on-chain (Solana NFT) and one on the knowledge graph (DKG UAL).
+ *
+ * Run:
+ *   node examples/biomedical-research.js
+ *
+ * Prerequisites:
+ *   - Copy .env.example to .env and fill in PRIVATE_KEY
+ *   - Ensure your wallet has testnet TRAC and Base Sepolia ETH
+ *     TRAC faucet:     https://faucet.origintrail.io
+ *     ETH faucet:      https://www.alchemy.com/faucets/base-sepolia
+ */
+
+import DKG from '../index.js';
+import { BLOCKCHAIN_IDS } from '../constants/constants.js';
+import 'dotenv/config';
+
+const OT_NODE_HOSTNAME = 'https://v6-pegasus-node-02.origin-trail.network';
+const OT_NODE_PORT = '8900';
+const BLOCKCHAIN_NAME = BLOCKCHAIN_IDS.BASE_TESTNET;
+
+// IMPORTANT: Don't forget to add your PRIVATE_KEY to the .env file.
+const DkgClient = new DKG({
+    endpoint: OT_NODE_HOSTNAME,
+    port: OT_NODE_PORT,
+    blockchain: {
+        name: BLOCKCHAIN_NAME,
+        privateKey: process.env.PRIVATE_KEY,
+    },
+    maxNumberOfRetries: 300,
+    frequency: 2,
+    contentType: 'all',
+    nodeApiVersion: '/v1',
+});
+
+function divider() {
+    console.log('==================================================');
+    console.log('==================================================');
+    console.log('==================================================');
+}
+
+/**
+ * A biomedical research report structured as a schema.org/MedicalStudy.
+ *
+ * The `og:` prefix is a custom vocabulary namespace for OpenGenome-specific
+ * fields (confidence scores, Solana mint address, herb recommendations).
+ * All standard medical metadata uses schema.org types directly.
+ *
+ * PubMed citations are included as ScholarlyArticle references so the
+ * knowledge asset carries full source provenance on-chain.
+ */
+const researchContent = {
+    public: {
+        '@context': {
+            '@vocab': 'https://schema.org/',
+            og: 'https://opengenome.bio/schema/v1/',
+        },
+        '@id': 'urn:opengenome:analysis:1',
+        '@type': 'MedicalStudy',
+        name: 'Hantavirus Pulmonary Syndrome - OpenGenome Research #1',
+        description:
+            'AI-assisted biomedical research report identifying Hantavirus Pulmonary Syndrome ' +
+            'with supporting PubMed evidence and evidence-backed herbal adjunct recommendations.',
+        'og:analysisId': 1,
+        'og:primarySignal': 'Hantavirus Pulmonary Syndrome',
+        'og:confidenceScore': 87,
+        'og:signalStrength': 82,
+        'og:solanaMint': 'ExampleSolanaAddressHere',
+        'og:platform': 'https://opengenome.bio',
+        dateCreated: new Date().toISOString(),
+        studySubject: {
+            '@type': 'MedicalCondition',
+            name: 'Hantavirus Pulmonary Syndrome',
+            code: {
+                '@type': 'MedicalCode',
+                codeValue: 'B33.4',
+                codingSystem: 'ICD-10',
+            },
+        },
+        'og:herbs': [
+            {
+                '@type': 'Drug',
+                name: 'Ginger',
+                alternateName: 'Zingiber officinale',
+                'og:pmid': '21945235',
+                description: 'Anti-inflammatory and antiviral properties studied in respiratory conditions.',
+            },
+            {
+                '@type': 'Drug',
+                name: 'Turmeric',
+                alternateName: 'Curcuma longa',
+                'og:pmid': '37105214',
+                description: 'Curcumin shown to modulate cytokine response relevant to viral lung injury.',
+            },
+        ],
+        citation: [
+            {
+                '@type': 'ScholarlyArticle',
+                identifier: 'PMID:21945235',
+                url: 'https://pubmed.ncbi.nlm.nih.gov/21945235/',
+                name: 'Antiviral properties of ginger extracts against respiratory viruses',
+            },
+            {
+                '@type': 'ScholarlyArticle',
+                identifier: 'PMID:37105214',
+                url: 'https://pubmed.ncbi.nlm.nih.gov/37105214/',
+                name: 'Curcumin modulates cytokine storm in viral pneumonia models',
+            },
+        ],
+    },
+};
+
+(async () => {
+    const nodeInfo = await DkgClient.node.info();
+    console.log('======================== NODE INFO RECEIVED');
+    console.log(nodeInfo);
+
+    divider();
+
+    // Publish the knowledge asset to the DKG
+    const createResult = await DkgClient.asset.create(researchContent, {
+        epochsNum: 2,
+    });
+
+    console.log('======================== KNOWLEDGE ASSET CREATED');
+    console.log('UAL:', createResult.UAL);
+    console.log('View on DKG Explorer:');
+    console.log('https://dkg.origintrail.io/explore?ual=' + createResult.UAL);
+
+    divider();
+
+    // Retrieve the asset back to verify
+    const getResult = await DkgClient.asset.get(createResult.UAL);
+
+    console.log('======================== KNOWLEDGE ASSET RETRIEVED');
+    console.log(JSON.stringify(getResult, null, 2));
+
+    divider();
+
+    // SPARQL query: find all OpenGenome research assets
+    const queryResult = await DkgClient.graph.query(
+        `PREFIX schema: <https://schema.org/>
+         PREFIX og: <https://opengenome.bio/schema/v1/>
+
+         SELECT ?id ?signal ?confidence WHERE {
+             ?s a schema:MedicalStudy ;
+                og:analysisId ?id ;
+                og:primarySignal ?signal ;
+                og:confidenceScore ?confidence .
+         }`,
+        'SELECT',
+    );
+
+    console.log('======================== SPARQL QUERY RESULTS');
+    console.log(JSON.stringify(queryResult, null, 2));
+})();