celltypist for Spatial transcriptmoic data (visium HD) annotation?

[KunHHE]

hi @ChuanXu1, can I ask you if celltypist model is ok for Spatial transcriptmoic data (visium HD) cell type annotation? For visium HD data, we always perform segmentation to assign he bins to the segmented cell. Thank you!

[ChuanXu1]

@KunHHE, you can use CellTypist models to annotate Visium HD data at the bin level (e.g., 8 μm bins). While this may not capture cell-level resolution, it can provide a baseline for interpreting your segmented identities.