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layout home
title Open Scientific Intelligence (OSI) Hackathon for the Physical Sciences & Mathematics
description The Open Scientific Intelligence (OSI) Hackathon runs October 21–22, 2026. Formerly the LLM Hackathon for Materials Science & Chemistry — now covering agents, datasets, models, and scientific software across the physical sciences and mathematics.
keywords OSI Hackathon, Open Scientific Intelligence, LLM Hackathon, Materials Science, Chemistry, Physics, Mathematics, Physical Sciences, AI, Agents, Datasets, Scientific Software, Hybrid Hackathon, October 2026

Next edition · October 21–22, 2026

Open Scientific Intelligence Hackathon

Formerly the LLM Hackathon for Materials Science & Chemistry — now open to the physical sciences and mathematics. Covering agents, LLMs, datasets, benchmarks, models, scientific software and more against the biggest problems. Free, hybrid, and international.

26Oct
Osi
OSI Hackathon
October 21–22, 2026
{% include spectrum.html class="spectrum--glow spectrum--animated spectrum--live" %}
4th
edition · October 21–22, 2026
120
projects submitted in 2025 alone
4
community papers from past editions
16
on-site locations worldwide, plus virtual
Macro render of a glowing crystalline molecular lattice lit in sodium-amber and violet. Where language models meet the lattice

About the hackathon

2025 wrapped · 2026 set for October 21–22

Every year, this hackathon brings together scientists, mathematicians, and AI researchers from around the world for an intense sprint: build something real, in teams, across time zones and on-site locations.

Three editions in, the frontier has moved past language models alone — so the event has expanded in scope. As the Open Scientific Intelligence (OSI) Hackathon, the 2026 edition expands from materials science and chemistry to the physical sciences and mathematics, and welcomes submissions in: LLMs, autonomous agents, datasets, benchmarks, models, scientific software, and more.

The 2025 edition produced automated research assistants, novel data pipelines, and agentic lab workflows — explore them on the awards page. The next edition runs October 21–22, 2026registration is open. Join the Slack community to find teammates or propose hosting a site.

Three editions and counting

2023

The proof of concept

14 LLM applications built in a single sprint, published as a peer-reviewed paper in Digital Discovery.

Read the paper →
2024

Going global

34 projects across 7 on-site locations and a worldwide virtual cohort, documented on arXiv.

Read the paper →
2025

Agents arrive

Agentic workflows, tool use, and lab automation took center stage — 120 projects across 16 sites, documented on arXiv.

Read the paper →
2026

Next: the OSI Hackathon · October 21–22, 2026

The event becomes the Open Scientific Intelligence Hackathon — expanding to the physical sciences and mathematics, where LLMs, agents, datasets, models, and scientific software are all fair game. Registration is open now; the detailed schedule follows.

Register →

Featured videos

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2025 partners

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2026 sponsorship is open — see who's on board and how to join them.

Frequently asked questions

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