Try it in 2D first:
- 1st sub division is in half along R, which is the nuclear boundary
- get the total intensity for each of the subdivisions
- compare histograms
- stop if all intensity in one is the opposite of the other (need some threshold that means noise) . similarity of 0
- If you have a subdivision that is not above noise threshold, also halt analysis of that subdivision
- if two of the same subdivisions are sufficiently similar, continue to the next subdivision (division in half) and repeat these steps
Once we have a version of 2D in R we're happy with, we should compute it on a few other example structures from variance paper
question: then do it in each of the 3 dimensions independently or try doing subdivisions as "voxels"

Try it in 2D first:
Once we have a version of 2D in R we're happy with, we should compute it on a few other example structures from variance paper
question: then do it in each of the 3 dimensions independently or try doing subdivisions as "voxels"